Products

PEARLITOL
Mannitol USP/NF, EP, JP

Mannitol is a polyol manufactured by catalytic hydrogenation of starch, a natural raw material of vegetable origin. It occurs as a slightly sweet, white crystalline powder that gives a cooling sensation on dissolution in the mouth.

It has excellent stability, low hygroscopicity and good solubility in different solvents. It forms an ideal excipient for solid orals as well as injectable dosage forms and can be used for wet or dry granulation and direct compression. It also serves as a cryoprotective agent in freeze drying applications. Mannitol has low calorific values, is non-cariogenic and ideal for sugar-free formulations.

Crystalline Mannitol
 

Grade

Mean Diameter
(μm)

Type

Applications

 

Pearlitol 25 C
(Mannitol 25)

25

Extra-fine

Diluent for tablets, capsules and sachets, excipient for chemically unstable or moisture sensitive actives and orodispersible forms, freeze-drying carrier and sweetener for pharmaceutical chewing gums

Pearlitol 50 C
(Mannitol 35)

50

Fine

Pearlitol 160 C
(Mannitol 60)

160

Standard

Pearlitol PF
(Mannitol PFG)

-

Pyrogen-free

Diuretic-osmotic for injectable solutions and also for freeze dried injectables



Granular Mannitol
 

Grade

Mean Diameter
(μm)

Type

Applications

 

Pearlitol 100 SD

100

Spray-dried

Diluent for direct compression especially for chewable, effervescent and orodispersible tablets, ideal excipient for chemically unstable or moisture sensitive actives and also diluent for capsules and sachets

Granulated  types are also used as a neutral carrier base onto which actives are loaded

Pearlitol 200 SD

180

Pearlitol 300 DC

250

Granulated

Pearlitol 400 DC

360

Pearlitol 500 DC

520

 

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